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. 2013 Nov 20;8(11):e79727. doi: 10.1371/journal.pone.0079727

Table 1. Anthropometric and pulmonary function characteristics of mild (n=21), moderate (n=30), severe (n=26) and very severe (n=23) COPD patients.

Variables/Severity Mild (n=21) Moderate (n=30) Severe (n=26) Very severe (n=23) p
Gender (M/F) 15/6 21/9 19/7 15/8 -
Age (years) 65.9±10.4 67.8±8.7* 65.0±9.2 59.4±11.8 0.007
Weight (Kg) 67.7±13.0 71.5±11.4 71.0±14.0 61.1±11.3 0.3
Height (m) 1.64±0.09 1.65±0.08 1.65±0.08 1.61±0.08 0.3
BMI (Kg/m2) 25.1±4.4 26.2±3.8 25.9±3.9 23.5±4.4 0.1
FFM (Kg/m2) 18.3±3.2 17.9±2.5 17.2±2.5 16.4±1.6 0.5
CAT 12.0±6.6# 18.6±9.5 19.9±8.8 25.3±8.8 0.01
FEV1/FVC (L) 0.64±0.05# 0.53±0.1& 0.40±0.05$ 0.33±0.06 0.0001
CVF (L) 3.55±0.61# 2.98±0.79& 2.55±0.65$ 1.97±0.53 0.0001
FVC (%) 109.0±14.4# 92.8±16.3& 75.2±12.9$ 59.1±11.4 0.0001
FEV1 (L) 2.30±0.49# 1.56±0.44& 1.02±0.27$ 0.64±0.13 0.0001
FEV1 (%) 91.0±8.6# 62.2±10.2& 38.7±4.7$ 23.9±3.9 0.0001

M= male; F=female; BMI= Body mass index; FFM= fat free mass; CAT= COPD assessment test; FVC= forced vital capacity; FEV1= expiratory volume in the first second.

*Moderate vs. very severe; #mild vs. moderate, severe and very severe; &moderate vs. severe and very severe; $severe vs. very severe.