Table 1. Anthropometric and pulmonary function characteristics of mild (n=21), moderate (n=30), severe (n=26) and very severe (n=23) COPD patients.
Variables/Severity | Mild (n=21) | Moderate (n=30) | Severe (n=26) | Very severe (n=23) | p |
---|---|---|---|---|---|
Gender (M/F) | 15/6 | 21/9 | 19/7 | 15/8 | - |
Age (years) | 65.9±10.4 | 67.8±8.7* | 65.0±9.2 | 59.4±11.8 | 0.007 |
Weight (Kg) | 67.7±13.0 | 71.5±11.4 | 71.0±14.0 | 61.1±11.3 | 0.3 |
Height (m) | 1.64±0.09 | 1.65±0.08 | 1.65±0.08 | 1.61±0.08 | 0.3 |
BMI (Kg/m2) | 25.1±4.4 | 26.2±3.8 | 25.9±3.9 | 23.5±4.4 | 0.1 |
FFM (Kg/m2) | 18.3±3.2 | 17.9±2.5 | 17.2±2.5 | 16.4±1.6 | 0.5 |
CAT | 12.0±6.6# | 18.6±9.5 | 19.9±8.8 | 25.3±8.8 | 0.01 |
FEV1/FVC (L) | 0.64±0.05# | 0.53±0.1& | 0.40±0.05$ | 0.33±0.06 | 0.0001 |
CVF (L) | 3.55±0.61# | 2.98±0.79& | 2.55±0.65$ | 1.97±0.53 | 0.0001 |
FVC (%) | 109.0±14.4# | 92.8±16.3& | 75.2±12.9$ | 59.1±11.4 | 0.0001 |
FEV1 (L) | 2.30±0.49# | 1.56±0.44& | 1.02±0.27$ | 0.64±0.13 | 0.0001 |
FEV1 (%) | 91.0±8.6# | 62.2±10.2& | 38.7±4.7$ | 23.9±3.9 | 0.0001 |
M= male; F=female; BMI= Body mass index; FFM= fat free mass; CAT= COPD assessment test; FVC= forced vital capacity; FEV1= expiratory volume in the first second.
*Moderate vs. very severe; #mild vs. moderate, severe and very severe; &moderate vs. severe and very severe; $severe vs. very severe.