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. 2013 Nov 20;8(11):e80896. doi: 10.1371/journal.pone.0080896

Figure 7. Lesioned area of the PCT has a high expression of iNOS, IB4, and GFAP.

Figure 7

(A, B, C) Controls. (A) IB4; (B) iNOS; (C) GFAP. (C) GFAP-positive cells (arrows) with round nuclei and elongated cytoplasm are seen between nerve fibers of the control PCT. (D, E) Region P (bottom of the image) showing IB4 cells (insert in E) most intensively labeled. Distal to the lesion (top of the image), IB4 labeling is weak and few cells are seen. (F, G) iNOS expression in the lesion site. Note that iNOS and IB4 expression are mainly located in the PCT edge. (H, I) Region D of the tract showing several positive glial cells labeled for GFAP. They have a different morphology from resident glial cells and are seen aligned along the tract (insert). Scale bars: A, B = 50 µm; C = 40 µm; D, E = 50 µm; F, G = 40 µm; H, I = 30 µm.