Table 1. Input variables for epidemiologic and diagnostic parameters used in the base-case and sensitivity analyses.

Variable	Base Value	Range	Reference
Epidemiologic Parameters
TB prevalence among patients evaluated for TB (%)	6.4	0.5–15	Clinical data†
Proportion admitted during the daytime* (%)	24	10–50	Clinical data‡
No indication for admission except TB evaluation (%)	13	0–25	Clinical data‡
Number of annual inpatient TB evaluations	234	50–1000	Clinical data†
Diagnostic Parameters
Sensitivity of Xpert (%)
Smear-positive specimens	98	97–99	[19]
Smear-negative specimens	68	59–75	[19]
Specificity of Xpert (%)
Smear-positive specimens	98	92–100	[19]
Smear-negative specimens	98	97–99	[19]
Sensitivity of smear microscopy (%)	78.5	65–92	[24]
Specificity of smear microscopy (%)	98	97–99	[24]

Definition of abbreviations: TB = tuberculosis.

Legend:

^*Admitted between 9 am–4 pm.

^†Microbiology laboratory database and patient chart review.

^‡SFGH inpatient admission database.