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. 2013 Nov 20;8(11):e79143. doi: 10.1371/journal.pone.0079143

Table 2. Associations of sedentary behavior with markers of cardiometabolic risk in boys.

Continuous Cardiometabolic Risk WC (cm) BMI (Z-Score) Insulin (pmol/L) Glucose (mmol/L) HDL-C (mmol/L) Triglycerides (mmol/L) hs-CRP (mg/L)
Model 1
Sedentary Time (min/day) 0.010 (0.004, 0.016)* 0.040 (0.022, 0.059)* 0.002 (0.001, 0.004)* 0.001 (0.001, 0.002)* 0.0001 (−0.0004, 0.001) −0.0003 (−0.0007, 0.0001) 0.001 (−0.0002, 0.001) 0.004 (0.001, 0.006)*
Breaks in Sedentary Time (number/day) −0.020 (−0.059, 0.018) −0.093 (−0.215, 0.030) −0.006 (−0.017, 0.004) −0.004 (−0.010, 0.001) −0.002 (−0.005, 0.002) −0.001 (−0.004, 0.001) −0.004 (−0.008, 0.001) 0.002 (−0.014, 0.019)
Sedentary Bouts 1–4 Minutes (number/day) −0.065 (−0.100, −0.003)* −0.271 (−0.82, −0.161)* −0.019 (−0.028, −0.009)* −0.009 (−0.014, −0.005)* −0.002 (−0.005, 0.002) 0.001 (−0.002, 0.003) −0.005 (−0.010, −0.001)* −0.017 (−0.032, −0.002)*
Sedentary Bouts 5–9 Minutes (number/day) 0.069 (−0.076, 0.214) 0.357 (−0.103, 0.816) 0.010 (−0.028, 0.049) 0.006 (−0.015, 0.026) −0.004 (−0.018, 0.009) −0.008 (−0.018, 0.002) 0.003 (−0.015, 0.021) 0.077 (0.014, 0.139)*
Sedentary Bouts 10–14 Minutes (number/day) 0.594 (0.279, 0.908)* 2.526 (1.547, 3.506)* 0.158 (0.074, 0.241)* 0.078 (0.034, 0.121)* −0.010 (−0.041, 0.020) −0.026 (−0.048, −0.004)* 0.038 (−0.001, 0.076) 0.219 (0.084, 0.354)*
Sedentary Bouts 15–29 Minutes (number/day) 0.391 (0.059, 0.723)* 2.071 (1.034, 3.107)* 0.122 (0.034, 0.210)* 0.063 (0.017, 0.108)* 0.006 (−0.025, 0.038) −0.004 (−0.026, 0.019) 0.006 (−0.035, 0.047) 0.126 (−0.016, 0.269)
Sedentary Bouts 30+ Minutes (number/day) 0.6620 (−0.015, 1.256) 2.973 (0.962, 4.984)* 0.217 (0.048, 0.386)* 0.109 (0.021, 0.197)* −0.006 (−0.065, 0.053) −0.012 (−0.056, 0.031) 0.049 (−0.029, 0.127) 0.066 (−0.209, 0.341)
TV Viewing (hours/day) 0.465 (0.204, 0.726)* 0.904 (0.068, 1.740)* 0.088 (0.017, 0.160)* 0.041 (0.005, 0.078)* 0.024 (−0.0001, 0.049) −0.015 (−0.033, 0.003) 0.027 (−0.006, 0.060) 0.130 (0.017, 0.243)*
Computer/Video Game Use (hours/day) 0.687 (0.300, 1.073)* 1.629 (0.394, 2.863)* 0.058 (−0.049, 0.164) 0.066 (0.012, 0.119)* 0.032 (−0.004, 0.068) −0.043 (−0.069, −0.017)* 0.028 (−0.021, 0.076) 0.173 (0.007, 0.340)*
Model 2
Sedentary Time (min/day) 0.011 (−0.019, 0.041) 0.038 (−0.012, 0.087) −0.001 (−0.009, 0.008) 0.001 (−0.003, 0.004) 0.002 (−0.001, 0.005) −0.001 (−0.003, 0.001) −0.0004 (−0.004, 0.003) 0.003 (−0.009, 0.015)
Breaks in Sedentary Time (number/day) −0.057 (−0.106, −0.008)* −0.027 (−0.110, 0.057) −0.026 (−0.040, −0.012)* −0.002 (−0.008, 0.004) 0.001 (−0.005, 0.006) −0.001 (−0.005, 0.002) −0.005 (−0.011, 0.001) 0.005 (−0.014, 0.025)
Sedentary Bouts 1–4 Minutes (number/day) −0.063 (−0.111, −0.015)* −0.052 (−0.133, 0.030) −0.028 (−0.041−0.016)* −0.001 (−0.007, 0.005) −0.001 (−0.006, 0.004) −0.001 (−0.004, 0.003) −0.002 (−0.008, 0.004) −0.00002 (−0.019, 0.019)
Sedentary Bouts 5–9 Minutes (number/day) −0.048 (−0.245, 0.148) 0.080 (−0.244, 0.404) −0.039 (−0.094, 0.015) −0.007 (−0.030, 0.017) −0.005 (−0.025, 0.015) −0.011 (−0.025, 0.003) 0.005 (−0.019, 0.029) 0.047 (−0.029, 0.123)
Sedentary Bouts 10–14 Minutes (number/day) 0.473 (−0.006, 0.952) 0.334 (−0.468, 1.135) 0.169 (0.035, 0.302)* 0.001 (−0.057, 0.060) −0.041 (−0.091, 0.009) −0.030 (−0.065, 0.004) 0.018 (−0.041, 0.077) −0.073 (−0.262, 0.115)
Sedentary Bouts 15–29 Minutes (number/day) −0.165 (−–0.735, 0.405) −0.721 (−1.653, 0.211) 0.128 (−0.029, 0.285) −0.033 (−0.101, 0.035) −0.004 (−0.063, 0.055) 0.026 (−0.015, 0.067) −0.072 (−0.140, −0.003)* −0.279 (−0.498, −0.060)*
Sedentary Bouts 30+ Minutes (number/day) 0.321 (−0.411, 1.054) 0.194 (−1.021, 1.409) 0.153 (−0.051, 0.357) 0.038 (−0.050, 0.126) 0.004 (−0.070, 0.077) 0.007 (−0.046, 0.060) 0.017 (−0.072, 0.106) −0.171 (−0.447, 0.106)
TV Viewing (hours/day) 0.249 (−0.020, 0.519) −0.176 (−0.623, 0.272) 0.050 (−0.026, 0.125) 0.003 (−0.029, 0.036) 0.020 (−0.008, 0.048) −0.001 (−0.021, 0.018) −0.006 (−0.039, 0.027) 0.050 (−0.055, 0.155)
Computer/Video Game Use (hours/day) 0.485 (0.084, 0.886)* 0.799 (0.141, 1.457)* 0.016 (−0.097, 0.128) 0.031 (−0.017, 0.079) 0.013 (−0.028, 0.055) −0.041 (−0.070 −0.012)* 0.015 (−0.034, 0.064) 0.145 (−0.011, 0.300)

Model 1. Unadjusted analyses.

Model 2. Adjusted for accelerometer wear time, age, light and moderate-to-vigorous physical activity, total sedentary time (except when exposure), BMI Z-score (except when included in outcome), Tanner stage, parental income and level of education. Data are presented as beta coefficients (95% confidence intervals). n = 286.

Associations assessed using linear regression analysis. Data are presented as beta coefficients (95% confidence intervals). n = 286.

*

 = p<0.05.

Fasting insulin and plasma triglycerides have been transformed using a Box-Cox transformation.

Continuous cardiometabolic risk score was calculated by summing z-scores for insulin, glucose, triglycerides, negative HDL-cholesterol, blood pressure, BMI, and waist circumference for each participant.

BMI, body mass index; HDL-C, high density lipoprotein cholesterol; hs-CRP, high sensitivity c-reactive protein; MVPA, moderate-to-vigorous physical activity; TV, television; WC, waist circumference.