Figure 6.

Multi-dimensional prediction of future psychiatric hospitalizations due to suicidality. We analyzed in 42 bipolar subjects whether their SAT1 (spermidine/spermine N1–acetyltransferase 1), anxiety, mood and psychosis levels at the time of initial testing differentiated from those who had subsequent hospitalizations due to suicidality in the years since the testing occurred. Data in each dimension was normalized to a 0–100 scale (with the mood visual-analog scale (VAS) inverted, as the assumption was made that depressed mood states would more closely correlate with suicidality). The angle between dimensions was assumed to be 90°, and a simple Pythagorean distance from origin score was calculated. The distribution of this score in the test cohort was used to generate a receiver-operating characteristic curve for hospitalizations due to suicidality. (a) ROC curve. (b) Detailed results. (c) Three-dimensional visualization.