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. 2013 Oct 25;40(12):6899–6911. doi: 10.1007/s11033-013-2809-7

Table 8.

Selected combined effects of the IL-12A rs568408 and IL-12B rs3212227 polymorphisms in infected hemodialysis patients

Genotypes Group IIa (n = 55) Frequency (%) Group IIb (n = 182) Frequency (%) OR (95 % CI) P value
rs568408 GG and rs3212227 AA 24 (43.6) 74 (40.7) Referent
rs568408 GG and rs3212227 AC 7 (12.7) 53 (29.1) 4.6 (1.3–16.5)a 0.019c
rs568408 GG and rs3212227 AC 7 (12.7) 53 (29.1) Referent
rs568408 GG and rs3212227 CC 4 (7.3) 3 (1.6) 0.06 (0.008–0.4)a 0.005b
rs568408 AA and rs3212227 AA 2 (3.6) 1 (0.5) 0.5 (0.3–0.8)a 0.009c

aOdds ratio (OR) after adjustment for HBV surface antigen and chronic glomerulonephritis as a cause of renal replacement therapy

bSignificant after the Bonferroni correction for multiple comparisons (P < 0.006)

cNon-significant after the Bonferroni correction for multiple comparisons (P > 0.006)