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. Author manuscript; available in PMC: 2013 Nov 21.
Published in final edited form as: Cell Rep. 2013 Mar 21;3(3):10.1016/j.celrep.2013.02.025. doi: 10.1016/j.celrep.2013.02.025

Figure 4. Targeting of CesAB–EspA to the ATPase.

Figure 4

Although CesAB carries the targeting signal (colored in red), this is presented to EscN only when EspA is bound to CesAB by means of an induced conformational switch on CesAB. As a result, EscN recognizes the re-structured CesAB region and engages the CesAB–EspA complex.