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Behavior of MOG35–55-immunized mice in the open field test. The graphs show the total number of squares crossed (A), number of central squares entries (B), latency to rearing, and the relative linear regression (C,D) of control or MOG35–55-immunized mice assessed during a 5-min test. Values are expressed as mean ± SEM for six to eight mice and are representative of N = 5–6 separate experiments. *p < 0.05, **p < 0.01 indicate significant values compared to control mice.
