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. 2013 Oct 8;154(12):4607–4617. doi: 10.1210/en.2013-1737

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Copyright © 2013 by The Endocrine Society

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Figure 4. — Role of PLC/IP₃R in BPA rapid actions in female rat ventricular myocytes. A, Immunoblot of PLN threonine 17 (CAMKII site) phosphorylation and total PLN under control, BPA, and BPA + 1 μM U73122 treatment for 5 minutes. cont, control. B, Immunoblot of PLN threonine 17 phosphorylation and total PLN under control, BPA, and BPA + 5 μM xestospongin C treatment for 5 minutes. C, Immunoblot of RyR serine 2808 (PKA site) phosphorylation and total RyR under control, BPA, and BPA + 1 μM U73122 treatment for 5 minutes. The same results have been repeated three times for all experiments. BPA = 1 nM for all experiments. Xesto, xestospongin C.