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. 2013 Nov 13;36(12):4083–4090. doi: 10.2337/dc13-0496

Figure 2.

Figure 2

In vitro DPP4 release from paired SAT (white bars) and VAT (black bars) samples from lean and obese patients and in vivo DPP4 release from abdominal SAT samples from lean and obese men and women. A and B: DPP4 release was measured in paired adipose tissue specimens from 12 lean and 11 obese (5 with type 2 diabetes) patients by ELISA. *P < 0.05 compared with respective SAT sample or between groups as indicated. C–E: DPP4 was measured in arterialized blood and adipose tissue venous blood in lean and obese patients, and the net release of DPP4 was calculated (n = 27). C: Correlation of arterial DPP4 with DPP4 net release from adipose tissue, taking blood flow into account. Linear regression was performed with Spearman correlation. D: Net release of DPP4 from adipose tissue in lean and obese subjects with low arterial DPP4 (< 288 ng/mL, n = 14). *P < 0.05 by Mann-Whitney test. E: Net release of DPP4 from adipose tissue in men and women. *P < 0.05 by Mann-Whitney test. ND, nondiabetic.