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. Author manuscript; available in PMC: 2013 Nov 21.
Published in final edited form as: Syst Biol Reprod Med. 2010 Apr;56(2):10.3109/19396360903431638. doi: 10.3109/19396360903431638

FIGURE 6.

FIGURE 6

Temporal bounds of TSC differentiation. TSC differentiation is affected by stress globally on an mRNA level in a manner suggesting activation of early differentiation of lineages occurring temporally early after implantation. Consistent with the data for induction of PL1 protein, stress-induced PL1 mRNA (Liu et al. 2009). Similar to PL1, mRNA transcripts for other early placental hormones prolactin like protein- (PLP)M, PLPE and proliferin were also induced, but later placental hormone mRNA such as PLII, PLPA, PLPN, and others were not induced [Yamaguchi et al. 1994; Wiemers et al. 2003a; 2003b; Lin et al. 1997a; 1997b; Fassett et al. 2000; Fang et al. 1999].