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. Author manuscript; available in PMC: 2013 Nov 21.
Published in final edited form as: Lancet Neurol. 2013 May;12(5):10.1016/S1474-4422(13)70060-7. doi: 10.1016/S1474-4422(13)70060-7

Figure 4.

Figure 4

Examples of perivascular spaces (PVS) on MRI and histology. (a) 72 year old asymptomatic subject, right, T2-weighted image shows linear PVS in the plane of the image, and on left FLAIR shows WMH around the PVS; (b) 49 year old man with left internal capsule acute small deep infarct (not shown) on T2-weighted imaging shows a perivascular space extending from the periventricular to subcortical tissues and (c) on the corresponding FLAIR image, one WMH running longitudinally around the PVS. (d) PVS on histology (H&E x40) showing parenchymal tissue retraction from around small perforating vessels; these have been dismissed as a processing artefact but are typically seen in ageing brain sections, and often associated with SVD.