Table 3. Domains of PfEMPI proteins in P. falciparum.
Domain type | Number of domains |
---|---|
DBLα | 58 |
DBLβ-C2 | 18 |
DBLγ | 13 |
DBLδ | 44 |
DBUε | 13 |
DBL-X | 13 |
CIDRα | 51 |
CIDR non-α | 54 |
| |
Preferred pairings | Frequency |
| |
DBLα–CIDRα | 51/58 |
DBLβ–C2 | 18/18 |
DBLγ–CIDR non-α | 44/44 |
CIDRα–DBLδ | 39/51 |
CIDRα–DBLβ | 10/51 |
DBILβ–C2–DBLγ | 10/18 |
DBLγ–DBL-X | 8/13 |
Top, the total number of each DBL orCIDR domain type in intact var genes within the P. falciparum 3D7 genome. Bottom, the frequencies of the most common individual domain pairings found within intact var genes. The denominator refers to the total number of the first-named domains in intact var genes, and the numerator refers to the number of second-named domains found adjacent. See text for discussion of domain types.