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Effect of kinase inhibitors on neuroprotection of IRN against Aβ 25–35-induced neurotoxicity. Aβ 25–35-induced neurotoxicity was indicated by cell viability (a), LDH leakage (b), and the production of DNA fragmentation (c), respectively. Values given are the mean ± SEM (n = 6). # P < 0.001 compared with the control group; **P < 0.01 and ***P < 0.001 compared with the Aβ 25–35-treated control; & P < 0.05 and &&& P < 0.001 compared with the group treated with Aβ 25–35 and IRN (50 μM).
