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In vivo radiomitigation with LY294002 and PX-867. Female C57BL/6NTac mice (15 per group) were exposed to an LD50/30 dose (9.25 Gy) whole-body irradiation and then were injected intraperitoneally 4 hours (open symbols) or 24 hours (closed symbols) later with vehicle (▪), LY294002 (30 mg/kg) (○,●), or PX-867 (30 mg/kg) (△,▾). Mice were observed for the development of the radiation-induced hematopoietic syndrome. *P < 0.001. **P < 0.017.
