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Distribution of LEPR gene 668 A/G polymorphism and allele frequencies between obesity patients and controls.
| Genotype | Patients (n: 127) (%) |
Controls (n: 105) (%) |
P |
|---|---|---|---|
| AA | 50 (39) | 50 (47.6) | |
| GA | 56 (44) | 46 (43.8) | 0.05* |
| GG | 21 (16.5) | 9 (8.5) | |
| AA + GA : GG | 106 : 21 | 96 : 9 | 0.10 |
| I GA + GG : AA | 77 : 50 | 55 : 50 | 0.20 |
| Allele frequency | |||
| A | 156 (61.4) | 146 (69.5) | 0.08 |
| G | 98 (38.5) | 64 (30.4) |
*According to Bonferroni correction is not significant.
