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. Author manuscript; available in PMC: 2014 Mar 3.
Published in final edited form as: Structure. 2013 Sep 3;21(9):10.1016/j.str.2013.08.011. doi: 10.1016/j.str.2013.08.011

Figure 1.

Figure 1

Domain structure of p300 overlaid with mutations and truncations found in solid tumors and lymphoid neoplasms (Iyer et al., 2004; Pasqualucci et al., 2011). The catalytic core of p300 is a hotspot for cancer mutations.