Table 5.

Molecular functions associated with Network A

Cellular and molecular functions	Moleculesa	Representative subgroup	Moleculesb	P-valuec	P-value subgroupd
Cellular function and maintenance	25	Lymphocyte homeostasis	23	1.3E−23–1.2E−02	1.3E−23
Cellular development	27	T cell development	22	3.0E−23–1.2E−02	5.9E−23
Cell-to-cell signaling and interaction	23	Activation of T lymphocytes	15	3.6E−16–1.3E−02	3.6E−16
Cellular growth and proliferation	26	Proliferation of lymphocytes	18	3.8E−15–1.2E−02	9.4E−15
Cellular movement	18	Lymphocyte migration	13	5.0E−13–1.2E−02	5.0E−13

Transcripts in Network A were uploaded into the ingenuity pathways application (Ingenuity Systems, www.ingenuity.com). The software was used to identify the most significant molecular functions.

^aNumber of functional analysis molecules related to the pathway.

^bNumber of functional analysis molecules related to the representative pathway subgroup.

^cRange of significance for pathway subgroups. Significance was determined from a single test P-value calculated using the right-tailed Fisher's exact test.

^dSignificance for representative pathway subgroup.