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Effects of regorafenib on cell growth recovery in PLC/PRF/5 and HepG2 cell lines. The PLC/PRF/5 and HepG2 cell lines were cultured in regorafenib 5 μM for 72 h. The medium was then removed (T0), and the cells were cultured for the indicated further days (T1–T3) in drug-free medium and analyzed using the MTT assay. The percentage of recovery of the treated cells respect control (vehicle) cells (100 % at T3) was 100 and 60 % for PLC/PRF/5 and HepG2, respectively
