Table 1.
Saracatinib- resistant |
Saracatinib- sensitive |
|
---|---|---|
Colorectal cancer cell lines | ||
PIK3CA wild-type | 14 | 0 |
PIK3CA mutant | 6 | 3 |
P = 0.0474 | ||
Colorectal cancer explants | ||
PIK3CA wild-type | 13 | 0 |
PIK3CA mutant | 2 | 2 |
P = 0.0441 | ||
Combined (colorectal cancer cell lines and explants) | ||
PIK3CA wild-type | 27 | 0 |
PIK3CA mutant | 8 | 5 |
P = 0.0020 |
NOTE: P < 0.05 was considered significant.