Table 2. Effects of Packing Density on the Thermal Dissociation Kinetics of DNA-AuNPs.
| DNA
dissociation at 37 °C |
DNA
dissociation at 85 °C |
|||
|---|---|---|---|---|
| packing density | k37a (min–1) | f37b | k85a (min–1) | f85b |
| 190/AuNP | 1.2 × 10–5 | 1.5% | 4.5 × 10–4 | 40.4% |
| 175/AuNP | 9.0 × 10–6 | 1.1% | 5.0 × 10–4 | 43.6% |
| 150/AuNP | 8.0 × 10–6 | 1.0% | 5.3 × 10–4 | 45.3% |
| 123/AuNP | 5.8 × 10–6 | 0.8% | 5.7 × 10–4 | 47.2% |
| 90/AuNP | 3.5 × 10–6 | 0.4% | 5.6 × 10–4 | 46.7% |
a
Rate constant k was determined from the first order reaction rate equation: ln(1 – [released]/[total]) = kt, where t = 60–1200 min.
b
Final released fraction f: f = [released]/[total] at 1200 min.