Table 2.
SNP | Chr | BP (HG19) | Minor/Major | Group | Cases/Controls | MAF1 (controls) | MAF (cases) | OR2 (95% CI) | P3 |
---|---|---|---|---|---|---|---|---|---|
rs9858822 | 3 | 12411238 | C/A | All | 2152/2630 | 1.36 (1.16, 1.60) | 1.5×10−4 | ||
LA | 489/414 | 0.027 | 0.034 | 1.26 (0.72, 2.20) | 0.42 | ||||
JA | 725/799 | 0 | 0 | na | na | ||||
AA | 443/824 | 0.31 | 0.39 | 1.36 (1.15, 1.62) | 0.0005 | ||||
EA | 381/416 | 0.0036 | 0.0013 | 0.31 (0.03, 3.05) | 0.32 | ||||
NH | 114/177 | 0.0028 | 0.0044 | 2.65 (0.16, 44.7) | 0.50 |
EA: European Americans; AA: African Americans; JA: Japanese Americans; LA: Latinos; NH: Native Hawaiians.
MAF: minor allele frequency
OR for the minor allele
P-values were from log-additive models, adjusted for age, gender and racial/ethnic groups. No heterogeneity across ethnic groups was detected (Phet > 0.3)