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Physicochemical characteristics of cholesterol- and DPPC-based cationic liposomes after mixing with HA.
| Formulation | Molar ratio | HA/liposomes | |||
|---|---|---|---|---|---|
| Zave (nm) | pdi | ZP (mV) | LE HA (%) | ||
| DDA:DPPC | 1:1 | 207 (±11) | 0.44 (±0.02) | +44 (±3.3) | 76 (±2) |
| DDA:Chol | 1:1 | 179 (±2) | 0.09 (±0.01) | +46.5 (±1.2) | 78 (±3) |
| eDPPC:DPPC | 1:1 | 150 (±5) | 0.13 (±0.02) | +47.8 (±1.4) | 68 (±3) |
| eDPPC:Chol | 1:1 | 166 (±4) | 0.10 (±0.02) | +45.5 (±0.9) | 79 (±1) |
Results are expressed as average ± standard deviation (n = 3 independent batches).
