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. Author manuscript; available in PMC: 2013 Nov 21.
Published in final edited form as: Int J Obes (Lond). 2012 Sep 4;37(6):10.1038/ijo.2012.142. doi: 10.1038/ijo.2012.142

Table 1.

Studies examining the relationship between sleep and sleep-disordered breathing during pregnancy with gestational diabetes risk

Author Qiu et al.42 Facco et al.41 Reutrakul et al.43
Sample size n = 1290 n = 189 n = 169
EGA at assessment 18 weeks First assessment: 13.8 weeks 26.2 weeks
Second assessment: 30.2 weeks
Parity Nulliparous and multiparous Nulliparous Unspecified
Method of assessment Interview Questionnaire Questionnaires
Measures
  • Duration of sleep during pregnancy

  • Prepregnancy sleep duration

  • Frequency of snoring

  • OGTT results

  • Duration of sleep during pregnancy

  • Snoring and frequency of snoring

  • OGTT results

  • Daytime sleepiness

  • Snoring assessment

  • Sleep quality

  • Nocturia, nocturnal enuresis and interruption of sleep

  • OGTT results

Outcome
  • Increased GDM risk among short sleeper (≤4 h per night) compared with regular sleeper (9 h per night)

  • Snoring was associated with twofold increased risk of GDM

  • Overweight women who slept short or snored had the greatest risk of GDM

  • Short sleep duration and frequent snoring associated with elevated OGTT results

  • Greater incidence of GDM with both short sleep and frequent snoring

  • Sleep duration was inversely related to glucose levels

  • Each hour of reduced sleep resulting in 4% increase in glucose levels

  • Increased likelihood of GDM associated with increased risk of sleep-disordered breathing

  • Individuals with sleep-disordered breathing, short sleep and frequent snoring had elevated risk GDM

Abbreviations: EGA, estimated gestational age; GDM, gestational diabetes; OGTT, oral glucose tolerance test.