Skip to main content
. Author manuscript; available in PMC: 2013 Nov 21.
Published in final edited form as: Biochemistry. 2012 Jul 25;51(31):10.1021/bi300511w. doi: 10.1021/bi300511w

Figure 1.

Figure 1

(A) Mechanism of the IMPDH reaction. The covalent enzyme–thioimidate intermediate is shown as E-XMP*. B. anthracis numbering is used. (B) Inhibitors targeting human IMPDH.