Figure 2. Molecular confirmation of recombination in WT, but not xrcc2 mutant plants.

Schematic representation of the GU.US recombination tester locus (A) and Southern analysis (B) of DNA from plants grown in the absence (lanes 1 to 6) or presence of β-estradiol (lanes 7 to 10), digested with SacI (lanes 1,3,4,7,8) or SacI plus I-SceI (lanes 2,5,6,9,10). The blot was hybridized with a GUS-specific probe as indicated in panel (A). The recombined GUS gene has lost its I-SceI site and is seen as a single 2.5 kb SacI fragment only in DNA from WT plants grown in presence of β-estradiol (lanes 7 and 9). Col0: WT plants of Columbia ecotype.