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| Position | Type of amino acid | |
| Indian subcontinent clade | Arctic-related clade | |
| 60 | Met | Leu |
| 84 | Ser | Thr |
| 110 | Asp | Glu |
| 135 | Ser | Pro |
| 179 | Val | Ilea |
| 332 | Ala | Gly |
| 371 | Ala | Thr |
| 379 | Ile | Val |
| 407 | Thr | Ala |
Excludes virus sample 3878-10 which adopts Val at position 179.
