Table 2.
Incremental Cost-Effectiveness Ratios for Maternal Staphylococcus aureus Screening and Decolonization Before Cesarean Deliverya
| ICER by Probability of Staphylococcus aureus Colonization, $/QALY |
|||||||
|---|---|---|---|---|---|---|---|
| Screening/Wound Culture Method | 1% | 5% | 10% | 20% | 30% | 40% | 50% |
|
25% Probability of decolonization success |
|||||||
| Agar/agar | 10,631,077 | 1,313,767 | 922,940 | 402,799 | 283,477 | 203,473 | 179,303 |
| PCR/agar | 18,244,123 | 5,085,743 | 3,410,549 | 1,360,614 | 951,692 | 758,448 | 607,422 |
| PCR/PCR | 23,128,146 | 5,259,576 | 2,705,445 | 1,443,178 | 995,366 | 805,703 | 649,926 |
|
50% Probability of decolonization success |
|||||||
| Agar/agar | 3,942,569 | 869,499 | 344,783 | 184,171 | 110,492 |
79,069 (C–E) |
54,554 (C–E) |
| PCR/agar | 12,506,785 | 2,611,239 | 1,510,744 | 706,479 | 494,562 | 358,580 | 279,146 |
| PCR/PCR | 8,643,593 | 2,501,542 | 1,501,343 | 761,849 | 481,436 | 341,625 | 281,063 |
|
75% Probability of decolonization success |
|||||||
| Agar/agar | 1,739,106 | 486,301 | 195,540 |
91,616 (C–E) |
55,068 (C–E) |
38,768 (C–E) |
25,121 (C–E) |
| PCR/agar | 7,751,050 | 2,134,213 | 960,480 | 478,422 | 309,852 | 217,078 | 170,734 |
| PCR/PCR | 8,488,401 | 1,791,167 | 963,867 | 468,356 | 299,476 | 212,607 | 162,942 |
|
90% Probability of decolonization success |
|||||||
| Agar/agar | 1,512,341 | 434,147 | 174,660 |
69,714 (C–E) |
37,634 (C–E) |
19,491 (C–E) |
9993 (C–E) |
| PCR/agar | 9,726,700 | 1,700,280 | 804,716 | 367,620 | 245,711 | 172,807 | 133,869 |
| PCR/PCR | 14,427,708 | 1,482,124 | 776,970 | 377,815 | 230,870 | 165,887 | 128,213 |
ICER indicates incremental cost-effectiveness ratio; PCR, polymerase chain reaction; QALY, quality-adjusted life-year.
Cells with boldface values and delineated by (C–E) indicate scenarios in which the intervention was cost-effective when values below $50,000 to $100,000 per QALY were considered cost-effective.