Table 1.
Patient Characteristics (n = 44)
| Arm 1 (n = 14) | Arm 2 (n = 15) | Arm 3 (n = 15) | |
|---|---|---|---|
| Mean (SD) age, years | 67.1 ± 7.8 | 66.5 ± 8.5 | 64.4 ± 11.9 |
| Race, no. patients | |||
| African American | 0 | 1 | 0 |
| White | 13 | 13 | 15 |
| Unknown | 1 | 1 | 0 |
| Mean (SD) BSA, m2 | 2.18 ± 0.27 | 2.12 ± 0.18 | 2.14 ± 0.19 |
| ECOG PS score | |||
| 0 | 11 | 13 | 12 |
| 1 | 3 | 2 | 2 |
| Clinical stage, no. patients | |||
| D0 | 10 | 8 | 9 |
| D1 | 3 | 4 | 3 |
| D2 | 1 | 3 | 3 |
| LN mets | 1 | 1 | 1 |
| Bone mets | 0 | 2 | 3 |
| Gleason score | |||
| Unknown | 1 | 1 | 1 |
| ≤6 | 5 | 4 | 1 |
| 7 | 5 | 6 | 5 |
| 8 | 0 | 2 | 4 |
| 9 | 3 | 2 | 4 |
| 10 | 0 | 0 | 0 |
| Mean (SD) baseline T score | |||
| Lumbar spine | 1.06 ± 1.71 | 1.72 ± 1.85 | 0.77 ± 1.38 |
| Femoral neck | −0.42 ± 1.94 | −0.27 ± 1.11 | −0.27 ± 1.14 |
| Total proximal femur | 0.26 ± 1.61 | 0.36 ± 1.22 | 0.13 ± 0.85 |
| Trochanter | 0.69 ± 1.95 | 0.83 ± 1.49 | 0.26 ± 1.22 |
| Number of patients with low BMD at baseline | |||
| Osteopenia (T score, | 4 | 3 | 5 |
| −1.0 to −2.4) | |||
| Osteoporosis (T score, less than or equal to −2.5) | 2 | 1 | 0 |
Abbreviations: BMD = bone mineral density; BSA = body surface area; ECOG PS = Eastern Cooperative Oncology Group ECOG Performance Status; LN = lymph node.