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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Reprod Toxicol. 2013 Aug 27;0:10.1016/j.reprotox.2013.08.003. doi: 10.1016/j.reprotox.2013.08.003

Fig. 7.

Fig. 7

Over-expression of Nrf2 resulted in a significant decrease in ethanol-induced apoptosis in NCCs. NCCs transfected with control or Nrf2 expression vector were treated with 100 mM ethanol for 24 hours. Ethanol-induced apoptosis was determined by analysis of the cleavage and activity of caspase-3 (A, B) and TUNEL assay (D). Cell viability was determined by MTS assay (C). Data are expressed as fold change over control (A, B, D) or percentage of control (C) and represent the mean ± SEM of three separate experiments. * p < 0.05 vs. control. # p < 0.05 vs. EtOH.