Table 1. Results of manual and semi-automatic measurements of 33 subsolid nodules on CT.

	Semi-automatic measurements		Manual measurement		Difference
	mean	SD	Mean	SD	p-value
Observer 1 first
Diameter (mm)	11.2	3.3	12.2	3.7	<0.001
Volume (ml)	935	692	1201	934	<0.001
Mass (milligrams)	379	311	431	369	0.007
Observer 1 second
Diameter (mm)	10.8	3.8	12.2	3.7	<0.001
Volume (ml)	930	809	1201	934	0.001
Mass (milligrams)	378	341	431	369	0.02
Observer 2
Diameter (mm)	11.1	3.7	12.2	3.7	<0.001
Volume (ml)	985	797	1201	934	0.001
Mass (milligrams)	399	344	431	369	0.07

Differences are tested with the paired samples T test.