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. 2013 Nov 16;62(12):4043–4051. doi: 10.2337/db13-0785

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© 2013 by the American Diabetes Association.

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FIG. 4. — Lower values of AFT predict the rate of weight change in obese subjects and in individuals with a higher WC. Differing relationships between AFT (adjusted for age, sex, ethnicity, %BF, FFM, and FPG) and rate of percent body weight change in 204 obese subjects with a BMI ≥29 kg/m² (A, right) vs. 86 nonobese subjects with a BMI <29 kg/m² (A, left), as well as in 189 subjects with a WC above the sex-dependent threshold of ≥103 cm for men and ≥95 cm for women (B, right) compared with 101 subjects below the threshold (B, left). The median follow-up time is 6.6 years. Rate of weight change on the y-axis is calculated as the difference between follow-up and initial weight, normalized to initial weight and to follow-up time (i.e., rate of percent weight change), and is reported on a safe-logarithmic scale. A relatively linear rate of weight gain over time has been previously described in longitudinal studies of Native Americans (23). hrs, hours.