Fig 2.

Baseline tetramer staining of CD8⁺ (A) NY-ESO-1_157-165– and (B) MART-1_26-35–specific T cells as a percentage of total CD8 T cells on the ordinate, and response plus stable disease versus progression on the abscissa for 45 patients. (C) Changes from baseline to week 12 in tetramer staining of MART-1_26-35–specific T cells as a percentage of total CD8 T cells on the ordinate, with responder plus stable disease versus progression on the abscissa for 37 patients. (D) Dot plots showing CD4⁺/CD25⁺/CD127^lowFoxP3⁺ T regulatory cells (T_regs) as a percentage of total CD4 T cells on the ordinate, with responder plus stable disease versus progression on the abscissa.