Table 3.
Univariate Analysis of Any Grade 4-5 Toxicity
| Variable | No. of Events | % | P |
|---|---|---|---|
| Dose received, Gy | < .001 | ||
| ≤ 69.25 | 1 of 57 | 2 | |
| 75-85.5 | 5 of 18 | 28 | |
| Age, years | .41 | ||
| ≤ 60 | 1 of 24 | 4 | |
| > 60 | 5 of 51 | 10 | |
| Performance status | .054 | ||
| 0 | 6 of 46* | 13 | |
| 1 | 0 of 28* | 0 | |
| Radiation treatment time, days† | .16 | ||
| Bin assignment, rNTDmean | .06 | ||
| Pilot (NA) | 0 of 4 | 0 | |
| 1 (0.00-0.119) | 2 of 6 | 33 | |
| 2 (0.12-0.179) | 0 of 8 | 0 | |
| 3 (0.18-0.239) | 4 of 27 | 15 | |
| 4 (0.24-0.309) | 0 of 26 | 0 | |
| 5 (0.31-0.410) | 0 of 4 | 0 | |
| PTV, cm3† | .9 | ||
| Chemotherapy | .23 | ||
| Any | 3 of 54 | 6 | |
| None | 3 of 21 | 14 |
Abbreviations: NA, not applicable; PTV, planning target volume; rNTDmean, mean normalized tissue (lung) dose divided by normalized prescription dose.
*
Total No. of patients adds up to only 74 because of missing data.
†
Analyzed as a continuous variable.