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. 2013 Oct 21;31(34):4343–4348. doi: 10.1200/JCO.2013.51.5353

Table 4.

Univariate Analysis of Late Grade 4-5 Toxicity (all patients)

Variable P
Lung
    Mean .63
    V5 .48
    V20 .66
    V30 .37
    PTV, cm3 .41
Bronchial tree dose*
    Max .020
    Mean .072
    D1cc .012
    D2cc .007
    D3cc .004
Heart dose
    Mean .16
    V5 .44
    V50 .43
Esophageal dose
    Max .66
    Mean .74
    D1cc .72
    D2cc .80
    D3cc .80

Abbreviations: DXcc, maximum dose D such that X cm3 of the structure received a dose ≥ D, where D is measured in Gy; max, maximum; PTV, planning target volume; VX, percent volume receiving a dose of ≥ X Gy.

*

Proximal bronchial tree defined as per Radiation Therapy Oncology Group 0813.