Table A2.
Dose Assignment Schema
| Dose (Gy)* | EQD2 (Gy) | Estimated % NTCP Risk for Grade 2 Pneumonitis |
||||
|---|---|---|---|---|---|---|
| Bin 1 | Bin 2 | Bin 3 | Bin 4 | Bin 5 | ||
| 57 | 60 | 0-11 | 11-12 | 12-15 | 15-22† | 22-40† |
| 63.25 | 70 | 0-11 | 11-13 | 13-16† | 16-26 | 40-50 |
| 69.25 | 80 | 0-12 | 12-15 | 15-22 | 22-40 | 40-65 |
| 75 | 90 | 0-12 | 12-16† | 16-26 | 26-50 | 50-80 |
| 80.5 | 100 | 0-13† | 13-21 | 21-38 | 38-61 | 61-80+ |
| 85.5 | 110 | 10-21 | 15-23 | 26-50 | High | High |
Abbreviations: EQD2, equivalent dose for late effects (α/β = 3 Gy) if delivered in 2–Gy fractions; NTCP, normal tissue complication probability.
*
Prescription dose delivered over 25 fractions.
†
Indicate starting dose level for each bin.