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Adverse Events by Grade and Cohort
| COHORT | ||||||
|---|---|---|---|---|---|---|
| AE Classification | Grade | 1 (n=2) | 2 (n=3) | 3 (n=3) | 4 (n=3) | 5 (n=3) |
| Neutropenia | 1 | 1 | 1 | |||
| 2 | 1 | |||||
| 3 | 1 | 1 | 1 | 1 | ||
| 4 | 2 | 2 | ||||
| Anemia | 1 | 1 | ||||
| 2 | ||||||
| 3 | 1 | |||||
| Thrombocytopenia | 1 | 1 | 1 | |||
| 2 | ||||||
| 3 | ||||||
| Anorexia | 1 | 1 | 1 | 1 | ||
| 2 | 1 | 1 | ||||
| 3 | ||||||
| Vomiting | 1 | 2 | 1 | 2 | ||
| 2 | 1 | |||||
| 3 | ||||||
| Nausea | 1 | |||||
| 2 | 1 | |||||
| 3 | ||||||
| 3 | ||||||
| Diarrhea | 1 | 1 | 1 | 1 | ||
| 2 | 1 | 1 | ||||
| 3 | ||||||
| Weight loss | 1 | 1 | 2 | 1 | ||
| 2 | 1 | |||||
| 3 | ||||||
| Lethargy | 1 | 1 | 1 | |||
| 2 | 1 | 1 | ||||
| 3 | ||||||
| Neuropathy/lameness | 1 | 1 | ||||
| 2 | ||||||
| 3 | 1 | |||||
| Elevated ALP | 1 | |||||
| 2 | 1 | 1 | ||||
| 3 | 1 | |||||
| Elevated ALT | 1 | 1 | 1 | |||
| 2 | 1 | |||||
| 3 | 1 | 1 | ||||
| Epistaxis | 1 | 1 | ||||
| 2 | ||||||
| 3 | ||||||
