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. 2013 Oct 9;288(47):33873–33883. doi: 10.1074/jbc.M113.497701

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© 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 4. — E1015K Ca_V2. 1 is delivered to somato-dendritic and presynaptic compartments. Hippocampal neurons (6 days in vitro) transfected with WT or E1015K α1A were fixed after 5 days and probed with antibodies against MAP-2 or synaptobrevin-2. Note the distribution of both EGFP-α1A_WT EGFP-α1A_E1015K in the soma and dendrites immunolabeled for MAP-2. In addition, co-localization with synaptobrevin is observed in punctate-like structures demonstrating localization of both WT and the E1015K α1A in the presynaptic terminals. Scale bars, 10 μm.