Table 1.
Comparison of baseline and follow-up characteristics for Standard and Intensive treatment groups comprising 399 substudy patients.
| Variable | Baseline |
Follow-upa |
||||
|---|---|---|---|---|---|---|
| STD | INT | P-value | STD | INT | P-value | |
| (N = 200) | (N = 199) | (N = 200) | (N = 199) | |||
| Age (years) | 58.6 | 60.1 | 0.08 | |||
| Diabetes duration (years) | 10.3 | 12.4 | 0.007 | |||
| Baseline insulin | 47% | 48% | 0.80 | |||
| Male | 97% | 96% | 0.99 | |||
| Prior CV event | 38% | 37% | 0.79 | |||
| Hypertension | 73% | 68% | 0.26 | |||
| Race | ||||||
| Non-hispanic white | 58% | 56% | 0.73 | |||
| African-American | 21% | 22% | 0.79 | |||
| Hispanic | 17% | 19% | 0.68 | |||
| Current smoking | 16% | 20% | 0.35 | 11% | 13% | 0.43 |
| bFGF (pg/mL) | 16.0 | 14.2 | 0.50 | 8.1b | 8.0b | 0.95b |
| HbA1C (%) | 9.6 | 9.4 | 0.37 | 8.8 | 7.2 | <0.0001 |
| Systolic bp (mm Hg) | 130.3 | 131.5 | 0.51 | 128.2 | 124.5 | 0.03 |
| BMI (kg/m2) | 31.0 | 31.0 | 0.97 | 31.6 | 32.5 | 0.11 |
| Weight (lbs) | 212.6 | 213.2 | 0.88 | 216.4 | 224.3 | 0.06 |
| Waist/hip ratio | 0.99 | 0.99 | 0.87 | 1.00 | 0.99 | 0.24 |
| Total chol (mg/dL) | 183.2 | 182.6 | 0.90 | 163.4 | 155.7 | 0.03 |
| LDL chol (mg/dL) | 107.1 | 107.2 | 0.96 | 90.4 | 86.5 | 0.21 |
| HDL chol (mg/dL) | 36.4 | 37.6 | 0.25 | 38.9 | 40.1 | 0.32 |
| Triglycerides (mg/dL) | 208.7 | 184.1 | 0.16 | 177.8 | 148.5 | 0.006 |
| Serum creat (mg/dL) | 1.00 | 0.99 | 0.67 | 1.17 | 1.15 | 0.73 |
Results are means or percentages, and P-values are obtained from the comparison of the two treatment groups.
a Year 3 or previous non-missing value prior to year 3.
b Year 1 annual visit.Chol, cholesterol; creat, creatinine.