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BRAF mRNA expression and response to DTIC treatment. BRAF mRNA expression among patients experiencing a clinical benefit or progressive disease (PD) 3 months after commencement of DTIC chemotherapy. a BRAF expression in the total patient group, b data as presented in a, but limited to patients with tumors harboring wild-type BRAF, c similar analysis performed for tumors harboring BRAF V600 mutations. Asterisks denote significance levels: *p ≤ 0.05, **p ≤ 0.005
