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Estimated glomerular filtration rate over time in the two groups (A), and proportion of patients with estimated glomerular filtration rate ≥ 90 mL/min per 1.73 m2 at baseline and week 48 (B). LAM: Lamivudine; ADV: Adefovire; HBV: High hepatitis B virus; LdT: Telbivudine. GFR: Glomerular filtration rate
