TABLE 3.

Tumor characteristics and treatment courses for 11 patients with local recurrence

Site	Max size (cm)	Margin status	Grade	RT	CT	Time to first local recurrence (mo)	No. of local recurrences	Distant metastatic disease	Treatment of local recurrence	Status
UE-P	10	<1 mm	3	Pre	–	13	3	–	(1) EBRT/resection/brachytherapy, (2)  resection, (3) amputation	DOD
LE-P	15.5	>1 mm	3	Pre	Pre/post	16	1	Lung	Resection	DOD
LE-P	2.2	>1 mm	3	Pre/post	Post	45	1	Lung, brain	Resection	DOD
LE-P	10.5	Positive	3	Pre/post	–	36	2	Lung	(1) Resection + IORT, (2) amputation	DOD
Trunk	10	<1 mm	2	Pre/IORT	–	10	1	–	Open biopsy only	DOD
Breast	7	>1 mm	3	–	–	17	1	–	Resection/EBRT	NED
UE-D	2.5	Positive	3	–	–	6	1	–	Resection/brachytherapy	NED
UE-D (R)	5.5	Positive	2	–	–	12	2	–	(1) Resection, (2) amputation	DOD
LE-P (R)	2	Positive	3	–	–	85	3	–	(1) EBRT/resection/boost, (2) resection/  brachytherapy, (3) resection	NED
LE-D	1.5	<1 mm	2	–	–	8	1	–	EBRT/resection	NED
Trunk	6	Positive	3	Pre/post	–	35	1	–	EBRT only	NED

RT radiotherapy, CT chemotherapy, Pre/Post sequencing with surgery (before or after), UE-P upper extremity—proximal, UE-D upper extremity—distal, LE-P lower extremity—proximal, LE-D lower extremity—distal, (R) recurrent tumor, IORT intraoperative radiotherapy, EBRT external-beam radiotherapy, DOD dead of disease, NED no evidence of disease