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. Author manuscript; available in PMC: 2013 Nov 22.
Published in final edited form as: JAMA. 2012 May 9;307(18):10.1001/jama.2012.3954. doi: 10.1001/jama.2012.3954

Figure 3.

Figure 3

Meta-analyzed NRI (middle of data marker) and 95% CI (horizontal line) for the three outcomes based on eGFR categories overall and in subgroups according to demographic variables included in both equations and presence or absence of diabetes and hypertension (general population cohorts). The sizes of the data markers are proportional to the inverse of the variance of the NRIs. NRI was calculated as follows: NRI = Pr(down to lower eGFR category|events) + Pr(up to higher eGFR category|no events) – Pr(down to lower eGFR category|no events) – Pr(up to higher eGFR category|events). Positive NRI values favor the CKD-EPI equation.