Table 3.
Association of viral load measures on HPV 16 viral clearance.
Variable | Unadjusted (OR (95%CI)) | Adjusteda (AOR (95% CI)) |
---|---|---|
Higher study entry viral loada | 1.00 (0.88, 1.15) | 1.00 (0.84, 1.19) |
Index visit viral load | ||
≤2000 copies/104 cells | 1.0 | 1.0 |
>2000 copies/104 cells | 1.59 (0.61, 4.1) | 1.29 (0.39, 4.22) |
Higher baseline visit viral load | 0.99 (0.87, 1.1) | 0.87 (0.70, 1.1) |
Baseline visit viral load | ||
≤2000 copies/104 cells | 1.0 | 1.0 |
>2000 copies/104 cells | 0.95 (0.4, 2.3) | 0.42 (0.12, 1.4) |
Viral load change across visit-pair | ||
Increase | 1.0 | 1.0 |
Decrease | 3.16 (1.31, 7.65) | 5.62 (1.75, 17.9) |
>2 log increase | 0.41 (0.06,2.83) | 0.31 (0.03, 2.77) |
1–2 log increase | 1.11 (0.23,5.26) | 0.49 (0.05, 4.62) |
≤1 log change (+/−) | 1.0 | 1.0 |
1–2 log decrease | 2.39 (0.63, 9.02) | 2.61 (0.56, 12.6) |
>2 log decrease | 5.26 (1.66, 16.61) | 5.49 (1.40, 20.9) |
Adjusted for age, study site, contraceptive use, STI diagnosis during follow-up, cytology during follow-up, infection type.