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Phylogenetic relationship aspartic peptidase members of the A28 and A22 families from trypanosomatids. Peptidase sequences obtained from the MEROPS database release 9.6 [19] were aligned with the program ClustalW version 2.1 [122]; phylogram was constructed with the software MEGA version 5 [123] after 1,000 bootstraps with the neighbor-joining algorithm [124] (A) and (B) denote different subfamilies.
