Table 2.

Means, differences, and standard deviations of hormonal network biomarkers (μmol/L) for the tomato arm of the intervention (n=60)^†

Biomarker	Week 2	Week 12 mean (sd)	Difference‡	P§
IGF-1	129.1 (39.7)	132.0 (39.9)	2.9 (21.1)	.19
IGFBP-3	2,076.1 (441.5)	2,055.2 (426.2)	-20.9 (167.7)	.56
Estradiol	14.6 (5.2)	16.5 (9.7)	1.9 (9.0)	.19
SHBG	50.2 (24.7)	51.8 (25.0)	1.7 (6.5)	.08
c-peptide	4.6 (2.7)	4.6 (2.4)	.04 (2.0)	.55
Insulin	11.9 (11.6)	10.6 (7.0)	8.6 (.11)	.60

IGF-1 is insulin-like growth factor.

IGFBP-3 is insulin-like growth factor binding protein.

SHGB is sex hormone binding globulin.

^†One woman was excluded because of a late follow-up, and nine women were lost to follow-up.

^‡Difference is calculated as Week 12 - Week 2.

^§P-values were calculated using exact Wilcoxon signed rank tests (nonparametric mean pairwise tests).