Proteases |
AT |
Anticoagulation and antithrombosis |
HCF II |
Anticoagulation and antithrombosis |
Growth factors and cytokines |
FGF-1 |
Cell proliferation, differentiation, morphogenesis and angiogenesis |
FGF-2 |
Same as FGF-1 |
VEGF |
Cell growth, morphogenesis and development |
HGF |
Haepatocyte regeneration, morphogenesis, cell motility, tumourigenesis and metastasis |
PF-4 |
Inflammation and wound healing |
IL-8 |
Pro-inflammatory cytokine |
γ-interferon |
Dimerization and modulation of proteolytic processing |
Enzymes |
ApoE |
Lipid transport, Alzheimer’s disease risk factor |
Annexin V |
Anticoagulant activity |
Heparanase |
Inflammation and metastasis |
Pathogen proteins |
HIV-1 gp120 |
Viral entry |
Tat |
Transactivating factor, primes cells for HIV infection |
HSV glycoproteinB and glycoproteinC |
HSV attachment to the host cell |
Adhesion proteins |
Vitronectin |
Cell adhesion and migration |
Fibronectin |
Cell adhesion and traction |
Selectins |
Adhesion, inflammation and metastasis |
Integrins |
Cell adhesion and signalling |