Table 2.

Global target genes prediction of miRNAs

	Putative targets of miRNAs and their functions
miRNA name	Apoptosis and proliferation	Cell cycle	DNA damage	DNA repair
miR-192	BAG1, BCL2L11, CUL3, CUL5, CYCS, DHCR24, DYRK2, RCC3, IGF1, MALT1, MAPK1, NGFR, NTRK2, PERP, PRKACB	ABCC3, APPL1, BCAT1, CCND2, CDC7, CUL3, CUL5, TRIP13, SFTPB, RNF8, RBL2, RB1, RAD1, E2F6, KLK10	DYRK2, XPA, ERCC3, MYO6, RAD1,	RNF8, PRNP, ATP2C1, BCAT1, CEBPG, DBT, IDS, NAT5, MAN2A2, SMC5,
miR-200b	APAF1, CBX4, BCL2, DLC1, HMOX1, MALT1, NOTCH1, PTEN, SORT1, XRCC2	AHR, BTRC, CDC14A, CDK2, CDK6, CLASP1, CTSB, E2F3, ETS1, FOXN3, ITGB1, NBN,	DYRK2, NBN, HMOX1, MRPS35, NPM1	UHRF1, UBE2V1, UBE2N, TTC5, SHPRH, RRM2B, MMP19, MMP16, ERCC8,
miR-424	IGF1R, BCL2L2, TRAF1, TLR1, SOX9, SMAD3, SMAD7, PIK3R1, PIK3R2, KRAS, IGF1R, BIK, CD28	E2F3, E2F7, CDK6, CDC23, BIRC5, APP, ABL1, MLH3, LATS2, KATNB1,HNF4A, HMGA2	XPC, TIPIN, RAD9A, RAD23B, PHLDA3,	ACACA, AGPAT2, ACSL1, MMP24, RNF8, MMP3, SSRP1, UBE2B, UNG, WDR33
miR-194	APC, FADD, TRAF6, SPPL3, SORT1, SIRT1, PRKRA, PRKCA, IL6R	CDK6, E2F6, DDX11, VPS36, TLK1, RAD51, SORT1, PPT1, HGSNAT	CEP63, WRN, GTF2H1, SIRT1, SP100	RBX1, ESCO2, MGEA5, PIGN, RAD51L, PPAT, CUL4B, BCCIP, ATM
miR-98	TP53, TNFSF10, TEX261, SARM1, MAP3K1, FAS, FASLG, CASP3, BCL2L1, TBX5, RNF7, HGF	E2F2, HMGA2, MAPK4, USP6, STAG3, PARD6B, IDS, E2F6, AURKA, AURKB, ABCB9	CEP63, RAD1, ERCC6, TP53, RAD9A,	ACSL6, AGPAT3, DCT, BCAT1, RNF8, SMUG1, ENPP4, POLQ, NAT12, HDHD1A, ALDOC
miR-212	APAF1, ERBB2IP, APC, API5, BCL10, BNIP2, BRCA1, DEDD, HIP1, KRAS, PML, SMAD3, TNFRSF10B	ZWINT, TEX11, RB1, PSMD12, NEDD9, MIS12, MAPK3, FBXO31, EP300, ARL3, GAS7, PSME3	BRCA1, DYRK2, MSH2, SIRT1, NBN	ASF1A, CSRP2BP, FUCA2, MMP16, PURB, SMC6, EPHX2, NONO, RAD50, HEXB, IDS