Fig 2.

The effect of combined with E10A and docetaxel on the growth of s.c. xenografts of human prostate cancer in nude mice. When 150-250 mm³ s.c. xenografts had formed, mice were randomized groups and then subjected to 4 weeks treatment. (A) Time-dependent evolution of tumour volume in athymic mice with PC-3 and DU-145 cells xenografts (n= 10). (B) Tumour weight estimate of antitumour effect (n= 10). Mice were killed after 4 weeks of treatment and tumours were resected and weighted. (C) Kaplan–Meier estimate of survival time (n= 10). Survival of mice injected with E10A in combination with docetaxel had a better survival survival rate compared with additional groups of mice included Ad-LacZ control, E10A alone, Ad-LacZ plus docetaxel (P < 0.001 by log-rank method).