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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Mayo Clin Proc. 2013 Feb;88(2):10.1016/j.mayocp.2012.11.007. doi: 10.1016/j.mayocp.2012.11.007

TABLE 2.

Bleeding Outcomes

Characteristic Patient groupa
P value RR (95% CI)b
Clopidogrel (n=40) Control (n=80)
Hemoglobin values
 Nadir, g/dL 9.1 (1.2) 9.0 (1.1) .64
 Delta, g/dL 3.0 (1.7) 3.5 (1.6) .08
 Delta >4 g/dL 11 (28) 25 (31) .67 0.88 (0.48-1.60)
Major bleeding event 2 (5) 3 (4) 1.00 1.33 (0.23-7.66)
Combined bleeding outcome 19 (48) 36 (45) .80 1.06 (0.70-1.58)
 pRBCs
  Total units 2.1 (2.1) 2.1 (3.5) .49
  Patients requiring >3 units 9 (23) 14 (18) .51 1.29 (0.61-2.71)
Total units of platelets 0 (0) 0.1 (0.5) .32
Total units of FFP 0 (0) 0.5 (1.9) .04
Vitamin K during hospitalization 0 (0) 12 (15) .008 NR

cryo = cryoprecipitate; FFP = fresh frozen plasma; pRBCs = packed red blood cells; RR = relative risk.

a

Values are mean (SD) or No. of patients (%).

b

RR only provided for categorical data.

NR: Relative risk not reported since no patient in the clopidogrel group received vitamin K during hospitalization